A powerful natural anti-inflammatory agent from Ayurvedic medicine
Standardised to contain 80% in boswellic acid
3 + 1 free
Boswellia serrata is a tree originally found in India highly valued on account of the resin extruded from its trunk when it is cut open. This resin is very popular in Ayurvedic medicine in which it has traditionally been used in case of, among other illnesses, arthritis, asthma and bronchitis. It has also been used to produce incense.
This precious resin contains a high percentage of boswellic acids, pentacyclic triterpenic acids with great anti-inflammatory power the effectiveness of which is attested to by various scientific studies. Boswellic acids act by inhibiting various pro-inflammatory molecules such as the enzyme 5-lipoxygenase, cyclooxygenase and the complement system.
Our concentrated extract of Boswellia serrata gum resin standardised to contain 80% in boswellic acids and is recommended as an anti-inflammatory agent, a painkiller, for allergies and for helping to reduce the inflammation associated with conditions such as rheumatoid arthritis, psoriasis, erythematous eczema, asthma and inflammatory illnesses of the intestines.
Thanks to its high concentration of boswellic acids the product is highly effective.
Boswellia: Detailed information
Description and origin
The Boswellia (Boswellia serrata) is a tree of the Burseraceae family native to India. It grows in mountainous regions of India, North Africa and the Middle East. Its trunk, on being cut open, exudes a resin known as “Salai guggul” or “Indian Olibanum” which is used in Ayurvedic medicine to relieve pain (1). This resin is collected in summer and autumn and is stored in bamboo baskets to eliminate acid and leave the resin to solidify. Once processed the gum-resin is classified according to smell, colour, form and size (2).
The Boswellia serrata is one of the most valuable plants of Ayurvedic medicine. Used for thousands of years its name in Sanskrit (“Gajabhakshya”) refers to the fact that elephants, animals renowned for their longevity and strength, were seen to consume this plant.
The gum obtained from the incision in the trunk has a pleasant smell and a slightly bitter taste and has been used as incense (“frankincense”) by the Romans, Greeks and Egyptians (2).
It has traditionally been used in Ayurvedic medicine in case of arthritis, injuries and strengthening the female hormone system (3).
The gum resin of the Boswellia serrata contains 30-60% resin and 5-10% essential oils with the rest being polysaccharides (~65% arabinose, galactose, xylose). The resinous part contains mono-, di- and triterpenes, pentacyclic triterpenic acids (boswellic acids) and tetracyclic triterpenic acids (2). It has a pleasant smell thanks to its essential oil content and the boswellic acids are responsible for its anti-inflammatory properties. The acid acetyl-11-keto-beta-BA (AKBA) is one of the most effective boswellic acids and is a powerful inhibitor of the enzyme 5-lipoxygenase, an enzyme involved in inflammatory processes (4-5).
The gum-resin of Boswellia serrata has various properties: it has an anti-inflammatory effect, regulates the levels of lipids in the blood, is a painkiller, acts as a hepatoprotector, and is anti-arthritic and anti-arteriosclerosis (2). In Ayurvedic medicine boswellia is seen as having diaphoresic properties (used to increase sweating), diuretic properties and is an emmenagogue (used to stimulate menstruation) (6).
Boswellic acids have anti-inflammatory properties which prevent the formation of leukotrienes by inhibiting the enzyme 5-lipoxygenase (7). Leukotrienes are eicosanoids (lipid molecules deriving from arachidonic acid) produced by white blood cells and are involved in inflammatory processes such as bronquial asthma and colitis.
These acids also act on other pro-inflammatory molecules such as cyclooxygenase and the complement system (5) and have shown their effectiveness on inflammatory illnesses such as asthma, rheumatoid arthritis and osteoarthritis. They inhibit the nuclear factor Kappa-B (NF-KB), a transcription factor involved in the inflammation response and in illnesses such as rheumatoid arthritis and bronquial asthma; and also inhibit human leukocyte elastase, a protease (enzyme which degrades peptide bonds of other proteins) released by inflammation and hypersensibility (7). It also has anti-allergic properties associated with the inhibition of the degranulation of mast cells, cells involved in allergic reactions (8).
A laboratory test showed the potential use of boswellia extracts in case of arthritis: there was a reduction of pro-inflammatory cytokines, an increase in the levels of interleukin-10 (anti-inflammatory cytokine) and a modulation of oxidative stress after the administration of boswellia extract (9).
Finally an analgesic effect has also been observed, with a study of healthy persons showing an increase in the pain threshold and of pain tolerance after the ingestion of extract of B. serrata (5).
- Micropropagation and non-steroidal anti-inflammatory and anti-arthritic agent boswellic acid production in callus cultures of Boswellia serrata Roxb. Nikam et al. (2013) Physiol Mol Biol Plants 19(1): 105–116.
- Boswellia serrata, a potential antiinflammatory agent: an overview. Siddiqui (2011) Indian J Pharm Sci 73(3): 255-261.
- The effects of aqueous extract of Boswellia Serrata on hippocampal region CA1 and learning deficit in kindled rats. Jalili et al. (2014) Research in Pharmaceutical Sciences 9(5): 351-358.
- The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APCMin/+ mice. Wang et al. (2014) Drug Discov Ther 8(1): 25-32.
- A randomized, double blind, placebo controlled, cross over study to evaluate the analgesic activity of Boswellia serrata in healthy volunteers using mechanical pain model. Prabhavathi et al. (2014) Indian J Pharmacol 46(5): 475-479.
- Fitoterapia. Vademécum de prescripción. Vanaclocha and Cañigueral (2003) Elsevier.
- A cosmeceutical formulation based on boswellic acids for the treatment of erythematous eczema and psoriasis. Togni et al. (2014) Clin Cosmet Investig Dermatol 7: 321-327.
- Principles and practice of phytotherapy. Bone and Mills (2013). Elsevier.
- Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis.Umar et al. (2014) Phytomedicine 21(6): 847-856.
Ingredients: Boswellia Consulting batch information
3 capsules contain: 900 mg of dry extract of boswellia gum resin (Boswellia serrata Roxb. Ex Colebr.) standardised to contain 80% boswellic acid (i.e. 720 mg).
Potato starch. Vegetable-based capsule: hydroxypropyl methylcellulose.
This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.
Use: Boswellia Consulting batch information
3 capsules per day with half a glass of water at mealtimes.
Not recommended for pregnant or lactating woman. Do not exceed the recommended daily dose.
Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.
Store in a cool dry place away from sunlight.
Quality: Boswellia Consulting batch information
FABRICATION AND GUARANTEE:
This food supplement is manufactured by a GMP-compliant laboratory (GMPs are the Good Manufacturing Practice guidelines for the European pharmaceutical industry).
Their active principle content is guaranteed through regular tests, which can be viewed online.