Kudzu

Helps to treat withdrawal symptoms

Standardised to contain 40% isoflavones and 12% daidzein

14,00 €

Kudzu
Made in France | Ref. CP40

1 unit

3 + 1 free

Description: Kudzu

Kudzu (Pueraria lobata (Willd.) Ohwi) has been used for thousands of years in traditional Chinese medicine in case of problems relating to alcohol addiction.

Kudzu root contains isoflavones (daidzein, puerarin, daidzin etc.) and has been proven effective in reducing nicotine consumption. These isoflavones also have anxiolytic activity that can help with other addictions, such as alcohol addiction.

Our kudzu extract is standardised to contain 40% isoflavones and 12% daidzein, ensuring the highest quality.

Detailed information

Description and origin

Kudzu (Pueraria lobata (Willd.) Ohwi) belongs to the leguminous vegetable family and is a climbing plant native to eastern Asia (China, Korea and Japan). Its stalks can grow up to 15 m long and form tuberous roots of up to 2 m long and 18-45 cm wide, while its flowers resemble those of the pea .

History

Kudzu root, also known as Gegen in China, has been used for thousands of years in traditional Chinese medicine for alcoholism and alcohol intoxication (1). There are records of the use of Pueraria lobata together with other plants in cases of alcohol intoxication dating from 600 AD (2). In the United States, kudzu was introduced in the 19th Century, and in the first half of the 20th Century farmers planted it to help reduce soil erosion. It is a rapid growth plant and is now considered an invasive plant in this country (3).

Composition

Kudzu root contains flavonoids, coumarins and isoflavones, including daidzein, genistein, daidzein, genistin and puerarin.

Benefits

Kudzu root is used primarily in case of alcohol addiction and withdrawal symptoms. It is also used to alleviate the symptoms of the menopause.

Studies

Kudzu root has been used to alleviate the symptoms of the menopause, due to its isoflavone content. One laboratory test demonstrated the positive effects of the isoflavones in kudzu on lipid and bone metabolism (decrease in bone mineral density loss) (4).

Various laboratory studies also support the use of kudzu to reduce alcohol consumption (6) and withdrawal symptoms (6-7). One double-blind pilot study demonstrated that the consumption of a kudzu root extract with standardised isoflavone content significantly reduced alcohol consumption in regular drinkers (8).

Research suggests that the mechanism of action of kudzu’s isoflavones to reduce alcohol consumption may be due to the regulation of enzymes involved in alcohol metabolism. Inhibiting an enzyme involved in the elimination of alcohol was found to increase levels of acetaldehyde, a toxic compound responsible for the onset of hangover (1), and which may therefore increase aversion to drinking (9).

Alcohol detoxification and its treatment with drugs often disrupt sleep (insomnia, decreased sleep quality etc.) and can lead to a relapse. A preliminary study in which standardised kudzu extract was supplied to participants (moderate drinkers), found that kudzu did not affect any of the parameters that influence sleep quality (total sleep duration, nighttime awakenings etc.), and so its use in case of alcohol dependency would have no undesirable side effects (2).

Finally, the isoflavones present in kudzu are reported to have anxiolytic properties (7, 10) and some research suggests that inhibition of the enzyme involved in alcohol metabolism may also have anxiolytic properties that could help alleviate both withdrawal symptoms and anxiety about stopping smoking (11).

Bibliography

  1. Penetar et al. (2012) Theisoflavonepuerarin reduces alcohol intake in heavy drinkers: a pilot study. Drug Alcohol Depend 126(1-2): 251–256.
  2. Bracken et al. (2011) Kudzu root extract does not perturb the sleep/wake cycle of moderate drinkers. J Altern Complement Med 17(10): 961-6.
  3. http://www.nature.org/ourinitiatives/habitats/forests/explore/kudzu.xml
  4. Lim et al. (2013) Effects of dietary isoflavones from Puerariae radix on lipid and bone metabolism in ovariectomized rats. Nutrients 5(7): 2734-46.
  5. Lukas et al. (2013) A standardized kudzu extract (NPI-031) reduces alcohol consumption in non treatment-seeking male heavy drinkers. Psycopharmacology (Berl.) 226(1): 65-73.
  6. Benlhabib et al. (2004) Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. J Med Food 7(2): 168-79.
  7. Overstreet et al. (2003) NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav 75(3): 619-25.
  8. Lukas et al. (2005) An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting. Alcohol ClinExp Res 29(5): 756-62.
  9. McGregor (2007) Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk. Alcohol 41: 469-478.
  10. Zeng et al. (2010) Effect of daidzein on anxiety, social behavior and spatial learning in male Balb/cJ mice. Pharmacol Biochem Behav 96(1): 16-23.
  11. Overstreet et al. (2009) A selective ALDH-2 inhibitor reduce anxiety in rats. Pharmacol Biochem Behav 94(2): 255-261.
Updated on 2019/05/29

1 capsule contain: 100 mg dry extract of kudzu root (Pueraria lobata (Willd.) Ohwi) standardised to contain 40% isoflavones (i.e. 40 mg) and 12% daidzein (i.e. 12 mg).

Other ingredients:

Potato starch, vegetable-based capsule: hydroxypropyl methylcellulose.

FOOD ALLERGENS:

This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.

DIRECTIONS:

1 capsule per day with half a glass of water at mealtime.

WARNINGS:

Not recommended for women in case of personal or family history of breast cancer. Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.

ADVICES:

Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.

STORAGE INSTRUCTIONS:

Store in a cool dry place away from light.

FABRICATION AND GUARANTEE:

This food supplement is manufactured by a GMP-compliant laboratory (GMPs are the Good Manufacturing Practice guidelines for the European pharmaceutical industry).
Their active principle content is guaranteed through regular tests, which can be viewed online.

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