Kudzu

Helps to treat withdrawal symptoms

Standardised to contain 40% isoflavones and 12% daidzein

16,00 €

Kudzu
Made in France | Expiration date (End Of): 04/2022
Lot: D13840 |
Ref. CP40

1 unit

3 + 1 free

Description: Kudzu

Kudzu (Pueraria lobata (Willd.) Ohwi) has been used for thousands of years in traditional Chinese medicine in case of problems relating to alcohol addiction.

Kudzu root contains isoflavones (daidzein, puerarin, daidzin etc.) and has been proven effective in reducing nicotine consumption. These isoflavones also have anxiolytic activity that can help with other addictions, such as alcohol addiction.

Our kudzu extract is standardised to contain 40% isoflavones and 12% daidzein, ensuring the highest quality.

Detailed information

Description and origin

Kudzu (Pueraria lobata (Willd.) Ohwi) belongs to the leguminous vegetable family and is a climbing plant native to eastern Asia (China, Korea and Japan). Its stalks can grow up to 15 m long and form tuberous roots of up to 2 m long and 18-45 cm wide, while its flowers resemble those of the pea .

History

Kudzu root, also known as Gegen in China, has been used for thousands of years in traditional Chinese medicine for alcoholism and alcohol intoxication (1). There are records of the use of Pueraria lobata together with other plants in cases of alcohol intoxication dating from 600 AD (2). In the United States, kudzu was introduced in the 19th Century, and in the first half of the 20th Century farmers planted it to help reduce soil erosion. It is a rapid growth plant and is now considered an invasive plant in this country (3).

Composition

Kudzu root contains flavonoids, coumarins and isoflavones, including daidzein, genistein, daidzein, genistin and puerarin.

Benefits

Kudzu root is used primarily in case of alcohol addiction and withdrawal symptoms. It is also used to alleviate the symptoms of the menopause.

Studies

Kudzu root has been used to alleviate the symptoms of the menopause, due to its isoflavone content. One laboratory test demonstrated the positive effects of the isoflavones in kudzu on lipid and bone metabolism (decrease in bone mineral density loss) (4).

Various laboratory studies also support the use of kudzu to reduce alcohol consumption (6) and withdrawal symptoms (6-7). One double-blind pilot study demonstrated that the consumption of a kudzu root extract with standardised isoflavone content significantly reduced alcohol consumption in regular drinkers (8).

Research suggests that the mechanism of action of kudzu’s isoflavones to reduce alcohol consumption may be due to the regulation of enzymes involved in alcohol metabolism. Inhibiting an enzyme involved in the elimination of alcohol was found to increase levels of acetaldehyde, a toxic compound responsible for the onset of hangover (1), and which may therefore increase aversion to drinking (9).

Alcohol detoxification and its treatment with drugs often disrupt sleep (insomnia, decreased sleep quality etc.) and can lead to a relapse. A preliminary study in which standardised kudzu extract was supplied to participants (moderate drinkers), found that kudzu did not affect any of the parameters that influence sleep quality (total sleep duration, nighttime awakenings etc.), and so its use in case of alcohol dependency would have no undesirable side effects (2).

Finally, the isoflavones present in kudzu are reported to have anxiolytic properties (7, 10) and some research suggests that inhibition of the enzyme involved in alcohol metabolism may also have anxiolytic properties that could help alleviate both withdrawal symptoms and anxiety about stopping smoking (11).

Bibliography

  1. Penetar et al. (2012) Theisoflavonepuerarin reduces alcohol intake in heavy drinkers: a pilot study. Drug Alcohol Depend 126(1-2): 251–256.
  2. Bracken et al. (2011) Kudzu root extract does not perturb the sleep/wake cycle of moderate drinkers. J Altern Complement Med 17(10): 961-6.
  3. http://www.nature.org/ourinitiatives/habitats/forests/explore/kudzu.xml
  4. Lim et al. (2013) Effects of dietary isoflavones from Puerariae radix on lipid and bone metabolism in ovariectomized rats. Nutrients 5(7): 2734-46.
  5. Lukas et al. (2013) A standardized kudzu extract (NPI-031) reduces alcohol consumption in non treatment-seeking male heavy drinkers. Psycopharmacology (Berl.) 226(1): 65-73.
  6. Benlhabib et al. (2004) Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. J Med Food 7(2): 168-79.
  7. Overstreet et al. (2003) NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav 75(3): 619-25.
  8. Lukas et al. (2005) An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting. Alcohol ClinExp Res 29(5): 756-62.
  9. McGregor (2007) Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk. Alcohol 41: 469-478.
  10. Zeng et al. (2010) Effect of daidzein on anxiety, social behavior and spatial learning in male Balb/cJ mice. Pharmacol Biochem Behav 96(1): 16-23.
  11. Overstreet et al. (2009) A selective ALDH-2 inhibitor reduce anxiety in rats. Pharmacol Biochem Behav 94(2): 255-261.
Updated on 2019/05/29
Serving size: 1 capsule
Servings per container: 60
INGREDIENTS:
Amount per serving
NRVs*
Dry extract of kudzu root (Pueraria lobata (Willd.) Ohwi)
100.00 mg
N/A†
Isoflavones (40%)
40.00 mg
N/A†
Daidzein (12%)
12.00 mg
N/A†
*NRVs: Nutrient Reference Values
†N/A: Not applicable

Other ingredients:

Potato starch, vegetable-based capsule: hydroxypropyl methylcellulose.

Food allergens:

This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.

Updated on 2020/04/20

DIRECTIONS:

1 capsule per day with half a glass of water at mealtime.

WARNINGS:

Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.

ADVICES:

Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.

STORAGE INSTRUCTIONS:

Store in a cool dry place away from light.

Updated on 2020/04/20

PRODUCT NAME

Kudzu

BOTANICAL NAME

Pueraria lobata (Willd.) Ohwi

REFERENCE

CP40

QUANTITY

60 capsules

BATCH NUMBER

D13840

EXPIRATION DATE

2022/04

MADE

In France

SERVINGS PER CONTAINER

60 servings

FABRICATION AND GUARANTEE:

This food supplement is manufactured by a GMP-compliant laboratory (GMPs are the Good Manufacturing Practice guidelines for the European pharmaceutical industry).

Their active principle content is guaranteed through regular tests, which can be viewed online.

The labelling of our products complies with Regulation (EU) No 1169/2011 of the European Parliament and of the Council of 25 October 2011 and its subsequent amendments, with the aim of ensuring a high level of consumer protection in relation to food information.

Our packaging complies with Regulation (EC) No 1935/2004 of the European Parliament and of the Council of 27 October 2004 and its subsequent amendments on materials and articles intended to come into contact with food, aiming to secure a high level of protection of human health and the interests of consumers.

CHARACTERISTICS:

VEGETABLE CAPSULES

NOT IRRADIATED

WITHOUT ADDITIVES

WITHOUT ALLERGENS

WITHOUT BPA

NO OMG

WITHOUT LACTOSE

VEGAN

PRODUCT ANALYSIS:

ORGANOLEPTIC QUALITY

SPECIFICATIONS

RESULTS

Appearance:
Powder
Conform with specifications
Colour:
Brownish yellow
Conform with specifications
Odour:
Characteristic
Conform with specifications

ANALYTICAL QUALITY

SPECIFICATIONS

RESULTS

Irradiation detection:
Not irradiated
Conform with specifications

MICROBIOLOGICAL QUALITY

SPECIFICATIONS

RESULTS

Plate count:
NMT 10000 cfu/g
Conform with European Pharmacopoeia 8.0
Yeasts and molds:
NMT 500 cfu/g
Conform with European Pharmacopoeia 8.0
E. coli:
Negative
Conform with European Pharmacopoeia 8.0
Salmonella:
Negative
Conform with European Pharmacopoeia 8.0
Enterobacteraceae:
NMT 100 cfu/g
Conform with European Pharmacopoeia 8.0

PRODUCT REGISTRATION:

Anastore is registered on the Food Safety Register of Food Business Operators, whose purpose is to protect public health and consumer interests, where the definitions provided for in Articles 2 and 3 of Regulation (EC) No 178/2002 and Article 2 of Regulation (EC) No 852/2004 of the European Parliament and of the Council, and their subsequent amendments, are applicable.

These Regulations lay down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety, in addition to laying down general rules in relation to the hygiene of foodstuffs.

Finally, Anastore notifies the placing on the market of its food supplements in accordance with the specific regulations of each country.

Registration QR Code


Registration declaration

HEAD OF THE QUALITY DEPARTMENT

Certificate issue date: 2020/04/24

Updated on 2020/04/20

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