Helps to treat withdrawal symptoms
Standardised to contain 40% isoflavones and 12% daidzein
Expiration date (End Of): 04/2023 |
Lot: D14687 | Ref. CP40
3 + 1 free
Ingredients: Kudzu Consulting batch information
†N/A: Not applicable
Potato starch, vegetable-based capsule: hydroxypropyl methylcellulose.
This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.
Kudzu (Pueraria lobata (Willd.) Ohwi) has been used for thousands of years in traditional Chinese medicine in case of problems relating to alcohol addiction.
Kudzu root contains isoflavones (daidzein, puerarin, daidzin etc.) and has been proven effective in reducing nicotine consumption. These isoflavones also have anxiolytic activity that can help with other addictions, such as alcohol addiction.
Our kudzu extract is standardised to contain 40% isoflavones and 12% daidzein, ensuring the highest quality.
Kudzu: Detailed information
Description and origin
Kudzu (Pueraria lobata (Willd.) Ohwi) belongs to the leguminous vegetable family and is a climbing plant native to eastern Asia (China, Korea and Japan). Its stalks can grow up to 15 m long and form tuberous roots of up to 2 m long and 18-45 cm wide, while its flowers resemble those of the pea .
Kudzu root, also known as Gegen in China, has been used for thousands of years in traditional Chinese medicine for alcoholism and alcohol intoxication1. There are records of the use of Pueraria lobata together with other plants in cases of alcohol intoxication dating from 600 AD2. In the United States, kudzu was introduced in the 19th Century, and in the first half of the 20th Century farmers planted it to help reduce soil erosion. It is a rapid growth plant and is now considered an invasive plant in this country3.
Kudzu root contains flavonoids, coumarins and isoflavones, including daidzein, genistein, daidzein, genistin and puerarin.
Kudzu root is used primarily in case of alcohol addiction and withdrawal symptoms. It is also used to alleviate the symptoms of the menopause.
Kudzu root has been used to alleviate the symptoms of the menopause, due to its isoflavone content. One laboratory test demonstrated the positive effects of the isoflavones in kudzu on lipid and bone metabolism (decrease in bone mineral density loss)4.
Various laboratory studies also support the use of kudzu to reduce alcohol consumption6 and withdrawal symptoms6, 7. One double-blind pilot study demonstrated that the consumption of a kudzu root extract with standardised isoflavone content significantly reduced alcohol consumption in regular drinkers8.
Research suggests that the mechanism of action of kudzu’s isoflavones to reduce alcohol consumption may be due to the regulation of enzymes involved in alcohol metabolism. Inhibiting an enzyme involved in the elimination of alcohol was found to increase levels of acetaldehyde, a toxic compound responsible for the onset of hangover1, and which may therefore increase aversion to drinking9.
Alcohol detoxification and its treatment with drugs often disrupt sleep (insomnia, decreased sleep quality etc.) and can lead to a relapse. A preliminary study in which standardised kudzu extract was supplied to participants (moderate drinkers), found that kudzu did not affect any of the parameters that influence sleep quality (total sleep duration, nighttime awakenings etc.), and so its use in case of alcohol dependency would have no undesirable side effects2.
Finally, the isoflavones present in kudzu are reported to have anxiolytic properties 7, 10 and some research suggests that inhibition of the enzyme involved in alcohol metabolism may also have anxiolytic properties that could help alleviate both withdrawal symptoms and anxiety about stopping smoking11.
- The isoflavone puerarin reduces alcohol intake in heavy drinkers: a pilot study. Penetar et al. Drug Alcohol Depend. 2012. 126(1-2): 251–256.
- Kudzu root extract does not perturb the sleep/wake cycle of moderate drinkers. Bracken et al. J Altern Complement Med. 2011. 17(10): 961-6.
- Kudzu: The Invasive Vine that Ate the South. The Nature Conservancy. 2019.
- Effects of dietary isoflavones from Puerariae radix on lipid and bone metabolism in ovariectomized rats. Lim et al. Nutrients. 2013. 5(7): 2734-46.
- A standardized kudzu extract (NPI-031) reduces alcohol consumption in non treatment-seeking male heavy drinkers. Lukas et al. Psycopharmacology (Berl). 2013. 226(1): 65-73.
- Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. Benlhabib et al. J Med Food. 2004. 7(2): 168-79.
- NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Overstreet et al. Pharmacol Biochem Behav. 2003. 75(3): 619-25.
- An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting. Lukas et al. Alcohol Clin Exp Res. 2005. 29(5): 756-62.
- Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk. McGregor. Alcohol. 2007. 41: 469-478.
- Effect of daidzein on anxiety, social behavior and spatial learning in male Balb/cJ mice. Zeng et al. Pharmacol Biochem Behav. 2010 96(1): 16-23.
- A selective ALDH-2 inhibitor reduce anxiety in rats. Overstreet et al. Pharmacol Biochem Behav. 2009 94(2): 255-261.
Use: Kudzu Consulting batch information
1 capsule per day with half a glass of water at mealtime.
Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.
Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.
Store in a cool dry place away from light.
Quality: Kudzu Consulting batch information
BOTANICAL NAMEPueraria lobata (Willd.) Ohwi
SERVINGS PER CONTAINER60 servings
FABRICATION AND GUARANTEE:
This food supplement is manufactured by a GMP-compliant laboratory (GMPs are the Good Manufacturing Practice guidelines for the European pharmaceutical industry).
The active principle content is guaranteed through regular tests.
HEAD OF THE QUALITY DEPARTMENT
Certificate issue date: 2021/04/27