Vitamin K2

Obtained through natural fermentation (MK-7)

Helps keep our bones healthy

Vitamin K2

PRINCIPAL INDICATIONS:

Bones, Cardiovascular (bloodstream), Joints (cartilage, inflammation).

21,00 €

Ref. DK07 In Stock

Health claims accepted by the following organisations:

Vitamin K contributes to normal blood clotting.

Vitamin K contributes to the maintenance of normal bones.

Description

Vitamin K is a fat-soluble vitamin that plays an essential role in blood clotting and bone health.

Our menaquinone-7 vitamin (MK-7) is a natural vitamin K2 obtained through fermentation.

Being 100% trans ensures high bioavailability and absorption that benefits our bones.

In addition, studies conducted with vitamin MK-7 have shown that this vitamin has anti-inflammatory and cardiovascular properties.

Vitamin K helps keep our bones healthy. If vitamin K intake in the diet is not adequate, the risk of fractures and osteoporosis may increase.

 


Detailed information

Vitamin K is a fat-soluble vitamin that was originally recognised for its role in the coagulation process (K comes from the German word “Koagulation”). There are two types of vitamin K: vitamin K1 (phylloquinone) and menaquinones (MKs or vitamin K2). Vitamin K 1 is found mainly in leafy green vegetables and vegetable oils, while vitamin K2 is found in products of animal origin and is produced through various bacterial fermentation processes (1).

In addition to its role in coagulation (vitamin K is needed for the functioning of many of the enzymes involved in the clotting cascade), vitamin K plays a fundamental role in bone health, as it is required for the activation of osteocalcin, the most abundant non-collagenous protein found in bone (2) that helps to fix calcium in the bone matrix, participating in bone mineralisation (3). This role in maintaining bone health has been demonstrated in various studies that observed a positive effect of vitamin K on bone mineral density and a reduced risk of fracture (4). In countries such as Japan, for example, use of vitamin K2 is approved for the osteoporosis (5).

Together with these properties, vitamin K2 promotes suppleness in the arteries by preventing the accumulation of calcium in the artery walls (3), helping to reduce cardiovascular problems.

Although vitamin K is fat-soluble, the body only stores a small amount, so stores of the vitamin can be depleted rapidly if there isn’t a regular supply through diet, while vitamin K deficiency increases the risk of fracture and osteoporosis (6). Low levels of vitamin K have also been linked to a greater predisposition to osteoarthritis in the hands and knees (7).

Our product: Menaquinone-7 (MK-7)

One dose of our product contains 105 μg (140% NRVs*) of menaquinone-7 (MK-7) (vitamin K2) produced through biotechnology (obtained through natural fermentation). Recently, a study also demonstrated the anti-inflammatory properties of our vitamin MK-7 (8), confirming another mechanism through which vitamin K2 aids cardiovascular health.

*NRVs: Nutrient Reference Values.

Bibliography

1. Inaba et al. (2015) Low-dose daily intake of vitamin K2 (Menaquinone-7) improves osteocalcin γ-carboxylation: a double-blind, randomized controlled trials. J Nutr Sci Vitaminol (Tokyo) 61(6): 471-80.

2. Hamidi et al. (2013) Vitamin K and bone health. J Clin Densitom 16(4):409-13.

3. Maresz (2015) Proper calcium use: Vitamin K2 as a promoter of bone and cardiovascular health. Integr Med (Encinitas). 2015 Feb; 14(1): 34–39.

4. Pearson et al. (2007) Bone health and osteoporosis: the role of vitamin K and potential antagonism by anticoagulants. Nutr Clin Pract 22(5): 517-44.

5. Katsuyama et al. (2004) Promotion of bone formation by fermented soybean (Natto) intake in premenopausal women. J Nutr Sci Vitaminol (Tokyo) 50: 114-120.

6. http://lpi.oregonstate.edu/mic/vitamins/vitamin-K

7. Shea et al. (2015) The association between vitamin K status and knee osteoarthritis features in older adults: The health, aging and body composition study. Osteoarthritis Cartilage 23(3): 370–378.

Composition

INGREDIENTS:

1 capsule contains: 52.5 mg of natural menaquinone-7 (MK-7) crystals, produced from biotechnology (obtained through natural fermentation), corresponding to 105 μg of vitamin K2 (140% NRVs*).

*NRVs: Nutrient Reference Values.

OTHER INGREDIENTS:

Maltodextrin, vegetable-based capsule: hydroxypropyl methylcellulose.

ALLERGENS:

This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.

FABRICATION AND GUARANTEE:

This food supplement is manufactured by a GMP-compliant laboratory (GMPs are the good manufacturing practice guidelines for the European pharmaceutical industry).
Their active principle content is guaranteed through regular tests, which can be viewed online.

Use

DIRECTIONS:

1 capsule per day with half a glass of water, after mealtime.

WARNINGS:

Consult your doctor in case of simultaneous use of anticoagulants. Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.

ADVICES:

Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist’s advice. For adult use only. Keep out of reach of young children.

STORAGE INSTRUCTIONS:

Store in a cool dry place away from sunlight.

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