Bromelain + Rutin

Phytoenzyme and anti-inflammatory antioxidant

50:1 bromelain extract derived from pineapple, and rutin extract from Japanese Pagoda Tree flower buds

27,00 €

In Stock
Delivery between 22/10 and 26/10! ?
Made in France | Expiration date (End Of): 04/2023
Lot: D14729 |
Ref. EA60
1 unit
3 + 1 free

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Ingredients: Bromelain + Rutin
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Serving size: 2 capsules
Servings per container: 30
INGREDIENTS:
Amount per serving
NRVs*
Bromelain 2500 GDU** (Ananas comosus (L.) Merr)
500.00 mg
N/A†
Rutin (Sophora japonica L.)
250.00 mg
N/A†
*NRVs: Nutrient Reference Values
†N/A: Not applicable

**GDU: Gelatin digesting Units.

Other ingredients:

Vegetable-based capsule: hydroxypropyl methylcellulose.

Food allergens:

This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.

Updated on 2021/05/05

Description: Bromelain + Rutin

The main active compound in pineapple1, bromelain is a phytoenzyme, a protein that catalyses (accelerates) chemical reactions in the body2.

The enzymes act on various substances by degrading them to produce energy (catabolism) or by synthesizing them to construct the cell (anabolism).

Bromelain therefore activates an anti-inflammatory mechanism. By inhibiting the synthesis of prostaglandins, molecules involved in immune response, bromelain inhibits inflammatory processes such as oedema and muscle pain1, 3-5.

In addition, as a proteolytic enzyme, it breaks down proteins by breaking down the peptide bonds linking the amino acids. This action increases plasmin in the body, an enzyme that inhibits the formation of another element associated with inflammation: arachidonic acid6.

Rutin is a bioflavonoid, a molecule typically found in certain plants that has strong anti-inflammatory and antioxidant activity.

It inhibits the synthesis of thromboxane A2, a vasoconstrictor compound involved in inflammation7, 8. It inhibits the formation of free radicals and helps to preserve the structure and function of cells8. This boosts the effects of bromelain, which is particularly sensitive to oxidants.

Our formula combines a standardised rutin extract from the Japanese Pagoda tree, an important plant in China, with an extract of bromelain from pineapple stem (50:1) at optimal quality: no GMOs, exceptional purity rate (95%) and proteolytic activity (2500 GDU/g).

Bibliographie

  1. Properties and therapeutic application of bromelain: a review. Pavan, R. et al. Biotechnol Res Int. 2012. 976203.
  2. Larousse médical. Naudin, C. Larousse. 1996.
  3. Efecto de la Bromelina en la Concentración Sérica y Ósea de Clindamicina. Moraya, Z., & Walberto, J. Tesis Doctoral. 2012.
  4. Bromelain Monograph. Altern Med Rev. 2010. 5(4). 361-8.
  5. Bromelain as a treatment for osteoarthritis: a review of clinical studies. Brien, S. et al. Evid Based complement Alternat Med. 2004. 1(3). 251-257.
  6. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review. Abdul Muhammad, Z., Ahmad, T. J Pak Med Assoc. 2017 67(1), 121-125.
  7. Medicinal and Aromatic plants. Gupta, R. K. CBS publishers and distributors. 2010. 234, 499.
  8. Mechanisms Involved in the Antiplatelet Activity of Rutin, a Glycoside of the Flavonol Quercetin, in Human Platelets. Joen-Rong Sheu, George Hsiao, Po-Hsiu Chou, Ming- Yi Shen and Duen-Suey Chou. J Agric Food Chem. 2004. 52(14). 4414-4418 .
Updated on 2021/05/06

Use: Bromelain + Rutin
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DIRECTIONS:

2 capsules per day with half a glass of water, divided into two doses, outside mealtimes.

WARNINGS:

Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.

ADVICES:

Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.

STORAGE INSTRUCTIONS:

Store in a cool dry place away from sunlight.

Updated on 2021/05/05

Quality: Bromelain + Rutin
loading Consulting batch information

PRODUCT NAME

Bromelain + Rutin

REFERENCE

EA60

QUANTITY

60 capsules

BATCH NUMBER

D14729

EXPIRATION DATE

2023/04

MADE

In France

SERVINGS PER CONTAINER

30 servings

FABRICATION AND GUARANTEE:

This food supplement is manufactured by a GMP-compliant laboratory. GMPs are the good manufacturing practice guidelines in force in the European pharmaceutical industry.

The active principle content is guaranteed through regular tests.

CHARACTERISTICS:

VEGETABLE CAPSULES

NOT IRRADIATED

WITHOUT ALLERGENS

WITHOUT BPA

NO OMG

WITHOUT LACTOSE

VEGAN

PRODUCT ANALYSIS:

ORGANOLEPTIC QUALITY

SPECIFICATIONS

RESULTS

Appearance:
Powder
Conform with specifications
Colour:
Yellowish Green
Conform with specifications
Odour:
Characteristic
Conform with specifications

ANALYTICAL QUALITY

SPECIFICATIONS

RESULTS

Irradiation detection:
Not irradiated
Conform with specifications

MICROBIOLOGICAL QUALITY

SPECIFICATIONS

RESULTS

Plate count:
NMT 10000 cfu/g
Conform with European Pharmacopoeia 8.0
Yeasts and molds:
NMT 100 cfu/g
Conform with European Pharmacopoeia 8.0
E. coli:
Negative
Conform with European Pharmacopoeia 8.0
Salmonella:
Negative
Conform with European Pharmacopoeia 8.0
Enterobacteraceae:
NMT 100 cfu/g
Conform with European Pharmacopoeia 8.0

PRODUCT REGISTRATION:

The notification of placing on the market of this product has been made under notification number AS 2081/106.

HEAD OF THE QUALITY DEPARTMENT

Certificate issue date: 2021/05/06

Updated on 2021/05/05

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