Bromelain + Rutin

50:1 bromelain extract derived from pineapple, and rutin extract from Japanese Pagoda Tree flower buds

Phytoenzyme and anti-inflammatory antioxidant

Bromelain + Rutin

27,00 €

Ref. EA60 In Stock

Health claims accepted by the following organisations:

The Commission E recommends bromelain for post-operative and post-trauma oedema.


The main active compound in pineapple (1), bromelain is a phytoenzyme, a protein that catalyses (accelerates) chemical reactions in the body (2).

The enzymes act on various substances by degrading them to produce energy (catabolism) or by synthesizing them to construct the cell (anabolism).

Bromelain therefore activates an anti-inflammatory mechanism. By inhibiting the synthesis of prostaglandins, molecules involved in immune response, bromelain prevents inflammatory processes such as oedema and muscle pain (1,3-5).

In addition, as a proteolytic enzyme, it breaks down proteins by breaking down the peptide bonds linking the amino acids. This action increases plasmin in the body, an enzyme that inhibits the formation of another element associated with inflammation: arachidonic acid (6).

Rutin is a bioflavonoid, a molecule typically found in certain plants that has strong anti-inflammatory and antioxidant activity.

It inhibits the synthesis of thromboxane A2, a vasoconstrictor compound involved in inflammation (7, 8). It prevents the formation of free radicals and helps to preserve the structure and function of cells (8). This boosts the effects of bromelain, which is particularly sensitive to oxidants.

Our formula combines a standardised rutin extract from the Japanese Pagoda tree, an important plant in traditional Chinese medicine, with an extract of bromelain from pineapple leaves (50:1) at optimal quality: no GMOs, exceptional purity rate (95%) and proteolytic activity (2500 GDU/g).



  1. Pavan, R. et al. (2012). Properties and therapeutic application of bromelain: a review. Biotechnology research international, 2012.
  2. Naudin, C. (1996). Larousse médical. Larousse.
  3. Moraya, Z., & Walberto, J. (2012). Efecto de la Bromelina en la Concentración Sérica y Ósea de Clindamicina.
  4. Bromelain Monograph. (2010). Alternative Medicine review. Volume 15, Number 4.
  5. Brien, S. et al. (2004). Bromelain as a treatment for osteoarthritis: a review of clinical studies. Evidence-based complementary and alternative medicine, 1(3), 251-257.
  6. Abdul Muhammad, Z., Ahmad, T. (2017). Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.. JPMA: Journal of the Pakistan Medical Association, 67(1), 121-125.
  7. Gupta, R. K. (2010). Medicinal and Aromatic plants. CBS publishers and distributors, 234, 499.
  8. JOEN-RONG SHEU, GEORGE HSIAO, PO-HSIU CHOU, MING-YI SHEN, AND DUEN-SUEY CHOU. Mechanisms Involved in the Antiplatelet Activity of Rutin, a Glycoside of the Flavonol Quercetin, in Human Platelets. J. Agric. Food Chem. 2004, 52, 4414-4418



2 capsules contain: 500 mg dry extract of pineapple stem (from Ananas comosus (L.) Merr) standardised to contain 100% bromelain* (i.e. 500 mg), 250 mg dry extract of Japanese pagoda tree flower (from Sophora japonica L.) standardised to contain 100% rutin (i.e. 250 mg).
*Proteolytic activity greater than 2500 GDU.


Vegetable-based capsule: hydroxypropyl methylcellulose.


This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.


This food supplement is manufactured by a GMP-compliant laboratory. GMPs are the good manufacturing practice guidelines in force in the European pharmaceutical industry.
Their active principle content is guaranteed through regular tests, which can be viewed online.



2 capsules per day with half a glass of water, divided into two doses, outside mealtimes.


Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.


Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.


Store in a cool dry place away from sunlight.

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