L-citrulline is a non-protein amino acid involved in arginine synthesis and in nitric oxide production. Nitric oxide is a molecule involved in vasodilation and that regulates different functions in the skeletal muscle, such as glucose intake and blood flow  (1).

When combined with malic acid, L-citrulline malate is obtained. In a study it was observed that consumption of L-citrulline malate prior to the completion of physical exercise helped to reduce fatigue and relieve muscle pain (1). A reduced feeling of fatigue after consuming L-citrulline malate was linked to an increase in production of ATP during exercise, and an increase in the phosphocreatine recovery rate after physical activity (1).

In addition, there are studies in which it has been observed that L-citrulline malate enhances physical performance (2-3), and during exercise increases the use of branched-chain amino acids (BCAAs), which are metabolised in the muscle to produce energy (4).

Our L-Citrulline DL-Malate (2:1) powder is derived from fermentation, is suitable for vegans and has a 100% purity grade.

Bibliography

1. Pérez- Guisado and Jakeman (2010) Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 24(5): 1215-22.
2. Glenn et al. (2016) Acute citrulline-malate supplementation improves maximal strength and anaerobic power in female, masters athletes tennis players. Eur J Sport Sci 16(8): 1095-1103.
3. Wax et al. (2016) Effects of supplemental citrulline-malate ingestion on blood lactate, cardiovascular dynamics, and resistance exercise performance in trained males. J Diet Suppl 13(3): 269-282.
4. Sureda et al. (2010) L-citrulline-malate influence over branched chain amino acid utilization during exercise. Eur J Appl Physiol 110(2):341-51.