Melatonin

Regulator of the biological clock

Guaranteed purity over 99%

5 Reviews

11,50 €

In Stock
Delivery between 07/12 and 09/12! ?
Made in France | Expiration date (End Of): 04/2023
Lot: D14811 |
Ref. AN30

1 unit

3 + 1 free

This product allows you to accumulate 11 loyalty points.  11 points = 0,66€.

Ingredients: Melatonin
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Serving size: 2 capsules
Servings per container: 60
INGREDIENTS:
Amount per serving
NRVs*
Melatonin (synthetic origin, purity 99% min.)
1.80 mg
N/A†
*NRVs: Nutrient Reference Values
†N/A: Not applicable

Other ingredients:

Maltodextrin, vegetable-based capsule: hydroxypropyl methylcellulose.

Food allergens:

This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.

Updated on 2021/05/03

Description: Melatonin

Health claims

Melatonin contributes to the alleviation of subjective feelings of jet lag.

Melatonin contributes to the reduction of time taken to fall asleep.

Melatonin production is highest during adolescence and decreases with age. Therefore, taking melatonin improves sleep quality and helps regulate our biological clock.

Melatonin naturally regulates sleep and has none of the side effects of conventional sleeping pills.

Melatonin relieves tension, relaxes the muscles, is naturally sleep inducing, promotes healthy sleep, diminishes grogginess after sleep and reduces night-time awakenings.

In addition, melatonin helps the body to adapt to changes in its biological clock, which helps to avoid jet-lag in travellers.

Sublingual melatonin acts effectively when rapidly absorbed through the buccal mucosa.

Detailed information

Insomnia is lack of sleep or decreased sleep quality. It is a fairly common disorder that may be due to various causes, such as stress, pathological factors, lifestyle, and it negatively affects the individual’s ability to function during the day. To help regulate the sleep cycle and promote rest, melatonin offers an alternative to traditional sleeping pills.

Melatonin is a hormone produced by the pineal gland from tryptophan and it is regulated by the light-dark cycle. This hormone has several functions: it helps to regulate circadian rhythm and sleep and waking processes, it acts as a neurotransmitter, and also has immunomodulatory and antioxidant properties.

Melatonin’s primary role in the body is regulating day and night cycles, or sleep-wake cycles. Darkness causes the body to produce more melatonin, signalling to the body to prepare for sleep. Conversely, light decreases melatonin production, making the body prepare for waking1.

Melatonin has a chronoregulatory function, to adjust the sleep phase and resynchronise the biological clock2: studies to investigate the effect of melatonin on sleep and circadian rhythm have found a clear link between melatonin and circadian rhythm. Melatonin therefore helps to induce sleep in people whose circadian rhythm is disrupted, and can be used in case of insomnia associated with jet lag and for shift workers3-4.

In addition to its effect on circadian rhythm and the sleep cycle, melatonin has an immunomodulatory and antioxidant function. Its immunomodulatory activity has been demonstrated in in vivo and in vitro studies, where it was seen to act in innate response specifically on the immune system5. Through its antioxidant activity, melatonin stimulates the synthesis of antioxidant enzymes such as superoxide dismutase and glutathione reductase6-7.

Bibliography

  1. A review of sleep disorders and melatonin. Zizhen Xie, Fei Chen, William A Li, Xiaokun Geng, Changhong Li, Xiaomei Meng, Yan Feng, Wei Liu, Fengchun Yu. Neurol Res. 2017 Jun;39(6):559-565.
  2. Guía de Práctica Clínica sobre Trastornos del Sueño en la Infancia y Adolescencia en Atención Primaria. 2011. Guías de Práctica Clínica en el SNS: UETS N.º 2009/8
  3. Role of melatonin in the regulation of human circadian rhythms and sleep. Cajochen et al. J Neuroendocrinol. 2003. 15(4): 432-7.
  4. Therapeutic applications of melatonin. Kostoglou-Athanassiou. Ther Adv Endocrinol Metab. 2013. 4(1): 13-24.
  5. Melatonin: buffering the immune system. Carrillo-Vico et al. Int J Mol Sci. 2013. 14(4): 8638-83.
  6. Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes. Pandi-Perumal et al. Neurotox Res. 2013. 23(3): 267-300.
  7. Melatonin redox activity. Its potential clinical applications in neurodegenerative disorders. Miller et al. Curr Top Med Chem. 2015. 15(2): 163-9.
Updated on 2021/03/17

Use: Melatonin
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DIRECTIONS:

2 capsules per day with half a glass of water, half an hour before bedtime.

WARNINGS:

The beneficial effect is obtained by consuming 1 mg of melatonin close to bedtime. Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.

ADVICES:

Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist’s advice. For adult use only. Keep out of reach of young children.

STORAGE INSTRUCTIONS:

Store in a cool dry place away from sunlight.

Updated on 2021/05/03

Quality: Melatonin
loading Consulting batch information

PRODUCT NAME

Melatonin

REFERENCE

AN30

QUANTITY

120 capsules

BATCH NUMBER

D14811

EXPIRATION DATE

2023/04

MADE

In France

SERVINGS PER CONTAINER

60 servings

FABRICATION AND GUARANTEE:

This food supplement is manufactured in accordance with GMPs, GMPs are the Good Manufacturing Practices according to current European Pharmaceutical Industry.

The active principle content is guaranteed through regular tests.

CHARACTERISTICS:

VEGETABLE CAPSULES

NOT IRRADIATED

WITHOUT ALLERGENS

WITHOUT BPA

NO OMG

WITHOUT LACTOSE

VEGAN

PRODUCT ANALYSIS:

ORGANOLEPTIC QUALITY

SPECIFICATIONS

RESULTS

Appearance:
Powder
Conform with specifications
Colour:
Off-White
Conform with specifications
Odour:
Characteristic
Conform with specifications

ANALYTICAL QUALITY

SPECIFICATIONS

RESULTS

Irradiation detection:
Not irradiated
Conform with specifications

MICROBIOLOGICAL QUALITY

SPECIFICATIONS

RESULTS

Plate count:
NMT 10000 cfu/g
Conform with European Pharmacopoeia 8.0
Yeasts and molds:
NMT 100 cfu/g
Conform with European Pharmacopoeia 8.0
E. coli:
Negative
Conform with European Pharmacopoeia 8.0
Salmonella:
Negative
Conform with European Pharmacopoeia 8.0
Enterobacteraceae:
NMT 100 cfu/g
Conform with European Pharmacopoeia 8.0

PRODUCT REGISTRATION:

HEAD OF THE QUALITY DEPARTMENT

Certificate issue date: 2021/05/07

Updated on 2021/05/03

Reviews and questions: Melatonin

Reviews

5 / 5 5 Reviews

Cynthia

Great product, value and delivery. Have used for a whole now.

Edward Tweddle

Excellent product and service

Lesley Emberson

I started to take Melatonin a few weeks ago as I’m going through my menopause and my insomnia and hot flushes were dreadful. After trying everything else and after researching I found out that women in their Menopause can lack melatonin which we need to help with our sleep, especially REM sleep. This product has worked wonders for me, although I’m still not sleeping through the night, I’m managing about 4hours and when I do wake, am managing to go back to sleep a lot easier.

Daphne Slater

This product is amazing. I haven’t slept this well in a long time.

Peter Little

excellent. reliable.quick.clear website. could have had an English translation of directions

Your questions

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Question
I am a coach Driver can I drive with this ?
Anastore
its effect is to help you fall asleep. Melatonin can cause drowsiness, so it should be used with caution if the effects of drowsiness may be associated with a safety risk.

Question
Is melatonin addictive?
Anastore
No, melatonin capsules are not addictive.

Miss suz dobson
What is the difference between sublingual melatonin and melatonin? Thanks Suz.
Anastore
The difference is the directions: 2 capsules per day with half a glass of water, half an hour before bedtime or 2 tablets a day to be melted under the tongue, 20 minutes before bedtime. Sublingual melatonin has a more direct effect.

David
Is this product licensed for use in France or other European countries? Thank you.
Anastore
Yes it is.

Question
Is there Ethanol in these tablets or alcohol
Anastore
Ingredients of Melatonine: Melatonin (synthetic origin, purity 99% min.), Maltodextrin, vegetable-based capsule: hydroxypropyl methylcellulose.