Adjuvant in sympomatic treatment of micturition disorders in Benign Prostatic Hyperplasia at stage I e II1
Extract standardised to contain 0.8% vegetable sterols
Expiration date (End Of): 11/2022 |
Lot: D14366 | Ref. LO50
3 + 1 free
Description: Nettle root
In Europe, nettle (Urtica dioica L.) has been used for medicinal purposes for centuries. It has traditionally been used to relieve conditions such as rheumatism, anaemia, eczema and nephritis.
Nettle root is now recommended for relieving lower urinary tract symptoms associated with benign prostatic hyperplasia, increasing urine volume and flow. Its anti-inflammatory and hypotensive action also gives it cardioprotective properties.
Nettle root is very rich in nutrients: it contains polysaccharides, vegetable sterols, triterpene acids, fatty acids, lignans and polyphenols.
Our nettle root extract is standardised to contain 0.8% vegetable sterols, guaranteeing maximum efficacy.
Nettle root: Detailed information
• Description and origin
Nettle (Urtica dioica L.) belongs to the Urticaceae family and is native to Asia and Europe. It can be found in temperate regions around the world. It grows in areas rich in nutrients, and is a perennial herbaceous plant that can grow up to 150 cm and blossoms in late spring and summer. Its stems and leaves are covered with stinging hairs that cause skin irritation on contact.
Nettle has a long history of use as a medicine, as a food source (the leaves and stems can be eaten in salads), a source of fibre and in cosmetics2.
There is evidence that in ancient Egypt, nettle infusion was used for lower back pain and arthritis, and its leaves and root have traditionally been used in case of disorders such as rheumatism, anaemia, eczema, nephritis, and as a diuretic3.
Nettle is rich in active principles. Its roots contain polysaccharides, sterols (beta sitosterol, hydroxy sitosterol and its glycosides), triterpene acids, fatty acids, lignans, polyphenols, ceramides, a mixture of isolectins (UDA: Urtica dioica agglutinin) and scopoletin (a coumarin)4, 5.
• Our extract
Extract name: Dry extract of nettle root standardised to contain 0.8% vegetable sterols.
Scientific name: Urtica dioica L.
Part used: Root
Anti-inflammatory, diuretic and for the symptoms of benign prostatic hyperplasia and high blood pressure5.
One dose of our product (2 capsules, 500 mg) provides 4 mg of vegetable sterols, equivalent to 3 g of fresh root.
Use of nettle root extract for symptoms of benign prostatic hyperplasia has been studied extensively in clinical trials6, 7. One of the main uses of nettle root is to relieve the symptoms of urinary disorders associated with mild to moderate benign prostatic hyperplasia (Alken stages I and II and Vahlensieck stages II and III): it reduces post-void residual urine and increases urine volume4, 5. A reduction in the plasma levels of SHBG (sex hormone binding globulin) has also been identified8.
One study identified a hypotensive effect in aqueous extract of nettle root, due to the vasorelaxant effect caused by endothelial nitric oxide production and the opening of potassium channels9.
Nettle has also been used in Europe and North America in case of inflammatory diseases such as osteoarthritis. Recent research has identified that lipophilic extract is effective in reducing inflammation10.
- Extracted from the European Commission compilation list, under EFSA validation (ID 3936).
- Phenolic compounds analysis of root, stalk, and leaves of nettle. Otles and Yalcin (2012) ScientificWorldJournal Vol 2012, Article ID 564367, 12 pages.
- Pharmacognostical review of Urtica dioica L. Joshi et al. (2014) Int J Green Pharm 8: 201-9
- Urtica dioica(L): an undervalued, economically important plant. Bish et al. (2012) Agric Sci Res J 2 (5): 250-252.
- A comprehensive review on the stinging nettle effect and efficacy profiles. Part II: Urticae radix. Chrubasika et al. (2007). Phytomedicine 14: 568–579.
- Fitoterapia. Vademécum de prescripción. Vanaclocha and Cañigueral (2003) 4ª Edición. Elsevier España.
- Principles and practice of Phytotherapy. Bone and Mills (2013). Elsevier.
- Manual de Fitoterapia. García and Solís (2011) Elsevier.
- Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies. Testai et al. (2002) J Ethnopharmacol 81: 105-109.
- Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders. Johnson et al. (2013) Phytomedicine 20 (2): 143–147.
Ingredients: Nettle root Consulting batch information
†N/A: Not applicable
Maltodextrin, anti-caking agent (E470b): magnesium salts of fatty acids. Vegetable-based capsule: hydroxypropyl methylcellulose.
This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.
Use: Nettle root Consulting batch information
2 capsules per day with half a glass of water at mealtimes.
Consult your doctor and / or pharmacist. Not recommended for pregnant or lactating women. Do not exceed the recommended daily dose.
Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.
Store in a cool dry place away from sunlight.
Quality: Nettle root Consulting batch information
PRODUCT NAMENettle root
BOTANICAL NAMEUrtica dioica L.
SERVINGS PER CONTAINER30 servings
FABRICATION AND GUARANTEE:
This food supplement is manufactured by a GMP-compliant laboratory GMPs are the good manufacturing practice guidelines for the European pharmaceutical industry.
Their active principle content is guaranteed through regular tests.
The labelling of our products complies with Regulation (EU) No 1169/2011 of the European Parliament and of the Council of 25 October 2011 and its subsequent amendments, with the aim of ensuring a high level of consumer protection in relation to food information.
Our packaging complies with Regulation (EC) No 1935/2004 of the European Parliament and of the Council of 27 October 2004 and its subsequent amendments on materials and articles intended to come into contact with food, aiming to secure a high level of protection of human health and the interests of consumers.
Anastore is registered on the Food Safety Register of Food Business Operators, whose purpose is to protect public health and consumer interests, where the definitions provided for in Articles 2 and 3 of Regulation (EC) No 178/2002 and Article 2 of Regulation (EC) No 852/2004 of the European Parliament and of the Council, and their subsequent amendments, are applicable.
These Regulations lay down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety, in addition to laying down general rules in relation to the hygiene of foodstuffs.
Finally, Anastore notifies the placing on the market of its food supplements in accordance with the specific regulations of each country.
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Certificate issue date: 2020/11/26