Organic Maitake (Grifola frondosa)

Strengthens the immune system

Standardised extract to contain 30% polysaccharides (15% beta-glucans)

24,00 €

Organic Maitake (<em>Grifola frondosa</em>)
Made in France | Expiration date (End Of): 01/2022
Lot: D13574 |
Ref. GN70

1 unit

3 + 1 free

Description: Organic Maitake (Grifola frondosa)

Maitake (Grifola frondosa (Dicks.: Fr.) S.F. Gray) has been one of the most prized mushrooms in Japan for thousands of years. It is consumed as food and has valuable medicinal properties due to its bioactive compounds.

Rich in nutrients, maitake contains polysaccharides and beta-glucans. These compounds have immunostimulatory properties and help to lower blood glucose levels.

Maitake can help improve and prevent symptoms of obesity, arteriosclerosis and diabetes caused by high cholesterol levels.

Maitake also has heart-healthy properties that help to reduce hypertension and LDL cholesterol levels.

Our organic maitake extract is standardised to contain 30% polysaccharides and 15% beta-glucans, guaranteeing maximum effectiveness.

Detailed information

Maitake: Description and origin

Maitake, grifola or leafy polypore (Grifola frondosa (Dicks.: Fr.) S.F. Gray) is a basidiomycetic fungus used as food as well as in traditional medicine in China and Japan (1). Large in size, maitake grows as a cluster of overlapping layers at the base of trunks or roots of oaks, elms and other trees. It is found in northeastern parts of Japan and also in temperate forests in Asia, Europe and eastern parts of North America (2).

Maitake: History

A mushroom used in the East for thousands of years, the scientific name of maitake (Grifola frondosa) refers to the griffin beast of Greek mythology – half lion, half eagle, while frondosa, means “leaf-like”. In Japanese, mai means to dance and take means mushroom (“dancing mushroom”), because its appearance resembles a butterfly dancing, and because it is said that when people found it they began to jump for joy. It is a very valuable mushroom and it is said that in feudal times it was worth its weight in silver (2).

Maitake: Composition

The maitake mushroom contains beta-glucans, a diverse group of high molecular weight polysaccharides that may constitute between 10-50% of its dry weight. It also contains 5’-nucleotidase, sphingosine ceramides (lipids), aminopeptidases (enzymes), fibre, proteins and microelements (1,3).

Maitake: Our extract

Extract name: Dry extract of organic maitake standardised to contain 30% polysaccharides and 15% beta-glucans

Scientific name: Grifola frondosa (Dicks .: Fr.) S.F. Gray

Part used: Fruiting body

Maitake: Benefits

The maitake mushroom has multiple properties: it has an immunomodulatory effect, reduces blood glucose and lipid levels, as well as acting as a hypotensive and antioxidant. It is also known for its use as an adjuvant in oncological processes (1,3-4).

Maitake: Usage, dosage

A daily dose equivalent to 4 g of fungus is recommended, divided in two doses per day.

Maitake: Studies

The maitake mushroom has immunostimulant properties (4-5). One clinical study in which maitake extract was administered to patients suffering from myelodysplastic syndrome** concluded that beta-glucan extract stimulated immune response to infection by bacteria (6). In another study, combined consumption of shiitake and maitake extracts produced a stimulation of immune response. (7).

Maitake also helps to lower cholesterol levels: it has been established that maitake intake promotes catabolism* of fats and has anti-atherogenic effects (protects against the accumulation of cholesterol in the artery walls) (8) by modulating various enzymes involved in the synthesis, absorption and catabolism of cholesterol (1).

Finally, maitake improves and prevents the symptoms of obesity and diabetes associated with high cholesterol levels (8). In addition, maitake’s polysaccharides help to lower blood glucose levels by improving insulin resistance (9).

 

*Catabolism: set of metabolic processes degrading substances to form simpler ones.

**Myelodysplastic syndrome: syndrome in which immature blood cells in bone marrow do not mature or become healthy blood cells (10).

 

Maitake: Bibliography

1. Ding et al. (2016) The mechanisms underlying the hypolipidaemic effects of Grifola frondosa in the liver of rats. Front Microbiol 7: 1186.

2. Mayell (2001) Maitake extracts and their therapeutic potential – a review. Altern Med Rev 6(1): 48-60.

3. www.fitoterapia.net

4. Guggenheim et al. (2014) Immune modulation from five major mushrooms: application to integrative oncology. Integr Med (Encinitas) 13(1): 32–44.

5. Kodama et al. (2004) Administration of a polysaccharide from Grifola frondosa stimulates immune function of normal mice. J Med Food 7(2): 141-5.

6. Wesa et al. (2015) Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 64: 237–247.

7. Vetvicka and Vetvickova (2014) Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts. Ann Transl Med 2(2): 14.

8. Sato et al. (2013) Plasma cholesterol and transcriptome in mice fed with G. frondosa. J Oleo Sci 62(12): 1049-1058.

9. Xiao et al. (2015) Hypoglycemic effects of Grifola frondosa (Maitake) polysaccharides F2 and F3 through improvement of insulin resistance in diabetic rats. Food Funct 6(11): 3567-75.

10.http://www.cancer.gov/espanol/tipos/mieloproliferativas/paciente/tratamiento-mielodisplasicos-pdq

Serving size: 2 capsules
Servings per container: 30
INGREDIENTS:
Amount per serving
NRVs*
Dry extract of maitake* (Grifola frondosa (Dicks.) Gray)
500.00 mg
N/A†
Polysaccharides (30%)
150.00 mg
N/A†
Beta-glucans (15%)
75.00 mg
N/A†
*NRVs: Nutrient Reference Values
†N/A: Not applicable

*From organic farming.

Other ingredients:

Maltodextrin*, vegetable-based capsule: hydroxypropyl methylcellulose.

Food allergens:

This product does not contain allergens (in accordance with Regulation (EU) No 1169/2011) nor genetically modified organisms.

Updated on 2020/01/27

DIRECTIONS:

2 capsules per day divided into two doses with half a glass of water, at mealtimes.

WARNINGS:

Not recommended if pregnant or lactating women. Do not exceed the recommended daily dose.

ADVICES:

Does not replace a varied and balanced diet and a healthy lifestyle. If you are undergoing medical treatment, seek your therapist's advice. For adult use only. Keep out of reach of young children.

STORAGE INSTRUCTIONS:

Store in a cool dry place away from light.

Updated on 2020/01/24

PRODUCT NAME

Organic Maitake (Grifola frondosa)

BOTANICAL NAME

Grifola frondosa (Dicks.) Gray

REFERENCE

GN70

QUANTITY

60 capsules

BATCH NUMBER

D13574

EXPIRATION DATE

2022/01

MADE

In France

SERVINGS PER CONTAINER

30 servings

FABRICATION AND GUARANTEE:

This food supplement is manufactured by a GMP-compliant laboratory (GMPs are the good manufacturing practice guidelines for the European pharmaceutical industry).

Their active principle content is guaranteed through regular tests, which can be viewed online.

The labelling of our products complies with Regulation (EU) No 1169/2011 of the European Parliament and of the Council of 25 October 2011 and its subsequent amendments, with the aim of ensuring a high level of consumer protection in relation to food information.

Our packaging complies with Regulation (EC) No 1935/2004 of the European Parliament and of the Council of 27 October 2004 and its subsequent amendments on materials and articles intended to come into contact with food, aiming to secure a high level of protection of human health and the interests of consumers.

Organic products at Anastore are produced in accordance with Council Regulation (EC) No 834/2007 of 28 June 2007 and its subsequent amendments on organic production and the labelling of organic products, with the aim of ensuring consumer confidence and protecting consumer interests.

CHARACTERISTICS:

ORGANIC FARMING

VEGETABLE CAPSULES

NOT IRRADIATED

WITHOUT ALLERGENS

WITHOUT BPA

NO OMG

VEGAN

PRODUCT ANALYSIS:

ORGANOLEPTIC QUALITY

SPECIFICATIONS

RESULTS

Appearance:
Powder
Conform with specifications
Colour:
Beige
Conform with specifications
Odour:
Characteristic
Conform with specifications

ANALYTICAL QUALITY

SPECIFICATIONS

RESULTS

Irradiation detection:
Not irradiated
Conform with specifications

MICROBIOLOGICAL QUALITY

SPECIFICATIONS

RESULTS

Plate count:
NMT 10000 cfu/g
Conform with European Pharmacopoeia 8.0
Yeasts and molds:
NMT 100 cfu/g
Conform with European Pharmacopoeia 8.0
E. coli:
Negative
Conform with European Pharmacopoeia 8.0
Salmonella:
Negative
Conform with European Pharmacopoeia 8.0
Enterobacteraceae:
NMT 100 cfu/g
Conform with European Pharmacopoeia 8.0

PRODUCT REGISTRATION:

Anastore is registered on the Food Safety Register of Food Business Operators, whose purpose is to protect public health and consumer interests, where the definitions provided for in Articles 2 and 3 of Regulation (EC) No 178/2002 and Article 2 of Regulation (EC) No 852/2004 of the European Parliament and of the Council, and their subsequent amendments, are applicable.

These Regulations lay down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety, in addition to laying down general rules in relation to the hygiene of foodstuffs.

Finally, Anastore notifies the placing on the market of its food supplements in accordance with the specific regulations of each country.

Registration QR Code


Registration declaration

HEAD OF THE QUALITY DEPARTMENT

Certificate issue date: 2020/01/27

Updated on 2020/01/24

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